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MemoPryl With Antidepressants: What Is the Risk?
MemoPryl with antidepressants is a combination to avoid without a prescriber's approval. One named herb, St. John's wort, can raise serotonin to a dangerous level when mixed with some antidepressants. Keep taking your prescribed medicine and ask your doctor or pharmacist first.
Prepared by the MemoPryl label deskUpdated · 4 min read

The question01
Can you take MemoPryl with antidepressants?
You should not take MemoPryl with antidepressants unless the prescriber agrees. No study tested the capsule with these medicines.
The concern is St. John's wort, one of the six names. It is studied for mild to moderate depression, not for memory (NCCIH, St. John's wort), and it acts on the same chemistry as many antidepressants.
- 1PhosphatidylserineNot published per serving · Not known
- 2Ginkgo biloba leafNot published per serving · Not known
- 3N-Acetyl L-Carnitine HClNot published per serving · Not known
- 4St. John's wortNot published per serving · Not known
- 5Brahmi / Bacopa monnieriNot published per serving · Not known
- 6L-glutamineNot published per serving · Not known
Names only: no amounts are published. Supplement labels must list each ingredient with its amount (21 CFR 101.36, supplement labels), so the bottle itself is the check.
The risk02
What is serotonin syndrome?
Serotonin syndrome is a dangerous build-up of serotonin that can follow mixing St. John's wort with certain antidepressants. It needs urgent care (NCCIH, St. John's wort in depth).
| Sign | Action |
|---|---|
| Agitation, fast heartbeat, diarrhea | Call a doctor now |
| High fever, hallucinations, high blood pressure | Call 911 |
Other medicines03
Does St. John's wort affect other medicines too?
St. John's wort affects many other medicines, including birth control pills, warfarin and some HIV and heart drugs. It can weaken them (NCCIH, herb-drug interactions).
It can also make skin more sensitive to sun (NCCIH, St. John's wort in depth).
Next step04
What should you do if you take an antidepressant and want MemoPryl?
Ask the prescriber of your antidepressant before starting, and never stop it on your own. Bring the bottle.
Show the list
Name every herb on the bottle.
Keep your dose
Take your antidepressant as directed.
Report changes
Call about any new symptom.
Read the St. John's wort page and the medicines guide.
If you order05
Should you order MemoPryl while on an antidepressant?
Not before your prescriber agrees. The price shows at checkout, and a 60-day window is reported; confirm the live listing.
FAQ06
Questions about St. John's wort and antidepressants
How long should I wait between stopping an antidepressant and starting a supplement?
Only your prescriber can say, and some medicines need a taper. Do not stop an antidepressant to try a supplement. Ask first, and keep taking it until told otherwise.
Can St. John's wort be used instead of an antidepressant?
Not on your own. It is studied for mild to moderate depression, but it is not a swap for a prescription. Talk to your doctor about low mood.
Do all antidepressants clash with herbal supplements?
No, but many can. Which ones matter depends on the drug, so a pharmacist should check each one against the herbs listed on the bottle you receive.
Who wrote this07
Written and reviewed by
Pages built from the label, the official site, the sales page and linked NIH, FDA, FTC and peer-reviewed sources.
Last updated . Find our editorial standards and how we check reviews. This website is run by a U.S. order-link partner, not by the maker of MemoPryl. This site earns a commission when you buy through our order links.
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